Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79360.1PFAM: Cell division protein FtsA domain; KEGG: tbo:Thebr_0568 cell division protein FtsA. (584 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.953
AEM80023.1
KEGG: tbo:Thebr_2324 cyanophycin synthetase; TIGRFAM: Cyanophycin synthetase; PFAM: Mur ligase, central; Carbamoyl phosphate synthetase, large subunit, ATP-binding; ATP-grasp fold, RimK-type; Mur ligase, C-terminal; Belongs to the MurCDEF family.
 
  
 0.888
AEM79005.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
 
 0.874
AEM78806.1
CheC, inhibitor of MCP methylation / FliN fusion protein; KEGG: tbo:Thebr_1273 flagellar motor switch protein FliN; TIGRFAM: Flagellar motor switch FliN; PFAM: Surface presentation of antigen (SpoA); CheC-like protein.
 
  
 0.679
sepF
Cell division protein sepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
 
 0.652
AEM78296.1
PFAM: Protein of unknown function DUF2225; KEGG: tbo:Thebr_1586 hypothetical protein.
 
     0.647
rny
2,3 cyclic-nucleotide 2-phosphodiesterase; Endoribonuclease that initiates mRNA decay.
   
  
 0.602
AEM78796.1
PFAM: Type IV pilus assembly PilZ; KEGG: thx:Thet_1230 type IV pilus assembly PilZ.
 
     0.591
AEM78798.1
Flagellar biosynthetic protein FlhF; TIGRFAM: Signal-recognition particle (SRP)-type GTPase; PFAM: Signal recognition particle, SRP54 subunit, GTPase; KEGG: tbo:Thebr_1265 flagellar biosynthetic protein FlhF; SMART: ATPase, AAA+ type, core.
 
  
 0.579
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
  
 0.575
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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