Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM79367.1KEGG: thx:Thet_1886 hypothetical protein. (525 aa)    
Predicted Functional Partners:
AEM79368.1
PFAM: Heat shock protein 70; KEGG: thx:Thet_1887 heat shock protein 70.
 
 
 0.937
AEM77826.1
KEGG: thx:Thet_0285 hypothetical protein.
 
  
 0.892
AEM79369.1
KEGG: thx:Thet_1888 beta-lactamase domain-containing protein.
 
    0.886
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
   
   0.820
AEM79971.1
YycH family protein; PFAM: YycH; KEGG: tit:Thit_2309 YycH family protein.
  
     0.764
AEM79366.1
Hypothetical protein; Manually curated; KEGG: thx:Thet_1885 hypothetical protein.
       0.760
AEM78913.1
PFAM: Domain of unknown function DUF2357; Protein of unknown function DUF524; KEGG: thx:Thet_1112 hypothetical protein.
  
     0.755
AEM79492.1
KEGG: tbo:Thebr_0489 peptidoglycan-binding domain 1 protein; PFAM: Peptidoglycan binding-like; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup.
 
     0.754
efp
Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
 0.749
AEM79365.1
KEGG: tbo:Thebr_0563 hypothetical protein.
       0.748
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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