Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM79369.1KEGG: thx:Thet_1888 beta-lactamase domain-containing protein. (614 aa)    
Predicted Functional Partners:
AEM79367.1
KEGG: thx:Thet_1886 hypothetical protein.
 
    0.886
AEM79368.1
PFAM: Heat shock protein 70; KEGG: thx:Thet_1887 heat shock protein 70.
 
   0.839
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.793
AEM79366.1
Hypothetical protein; Manually curated; KEGG: thx:Thet_1885 hypothetical protein.
       0.754
AEM79365.1
KEGG: tbo:Thebr_0563 hypothetical protein.
       0.748
AEM77826.1
KEGG: thx:Thet_0285 hypothetical protein.
  
 
 0.727
AEM79364.1
KEGG: tbo:Thebr_0564 integral membrane protein; TIGRFAM: Integral membrane protein 1906; PFAM: Integral membrane protein 1906.
       0.719
AEM78019.1
TIGRFAM: flagellar operon protein TIGR03826; KEGG: tbo:Thebr_1832 flagellar operon protein YvyF.
    
 0.615
AEM78245.1
KEGG: tit:Thit_0658 hypothetical protein.
    
 0.615
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.486
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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