Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79373.1Hypothetical protein; Manually curated; KEGG: tpd:Teth39_0540 phosphotransferase system, phosphocarrier protein HPr. (544 aa)    
Predicted Functional Partners:
AEM79091.1
KEGG: tbo:Thebr_0751 RNA polymerase sigma-54 factor, RpoN; TIGRFAM: RNA polymerase sigma factor 54; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54, core-binding; RNA polymerase sigma factor 54.
 
  
 0.902
AEM79644.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
 
 0.861
AEM79485.1
Manually curated; PFAM: Phosphotransferase system, fructose subfamily IIA component.
  
 
 0.809
AEM79374.1
PFAM: Protein of unknown function DUF1667; KEGG: tbo:Thebr_0554 hypothetical protein.
       0.745
AEM79376.1
PFAM: FAD dependent oxidoreductase; BFD-like [2Fe-2S]-binding region; KEGG: tbo:Thebr_0552 FAD dependent oxidoreductase.
       0.745
AEM79375.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tmt:Tmath_1779 FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
       0.744
AEM79860.1
PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase; KEGG: thx:Thet_2299 iron-containing alcohol dehydrogenase.
     
 0.639
AEM77989.1
KEGG: tbo:Thebr_1870 PTS system, N-acetylglucosamine-specific IIBC subunit; TIGRFAM: Phosphotransferase system, N-acetylglucosamine-specific IIBC component; Phosphotransferase system, glucose-like IIB component; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site.
  
  
 0.630
AEM79177.1
KEGG: thx:Thet_1715 pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region.
  
  
 0.629
AEM79372.1
KEGG: thx:Thet_1891 dihydroxyacetone kinase, DhaK subunit; TIGRFAM: Dihydroxyacetone kinase DhaK, subunit 1; PFAM: Dak kinase.
  
  
 0.560
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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