STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79378.1KEGG: tbo:Thebr_0550 MIP family channel protein; TIGRFAM: Aquaporin; PFAM: Major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (243 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
 
 
 0.989
AEM79379.1
PFAM: Glycerol-3-phosphate responsive antiterminator; KEGG: tbo:Thebr_0549 glycerol-3-phosphate responsive antiterminator.
 
  
 0.831
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.724
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 
 0.675
AEM77989.1
KEGG: tbo:Thebr_1870 PTS system, N-acetylglucosamine-specific IIBC subunit; TIGRFAM: Phosphotransferase system, N-acetylglucosamine-specific IIBC component; Phosphotransferase system, glucose-like IIB component; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site.
   
  
 0.639
AEM79370.1
KEGG: tbo:Thebr_0558 dihydroxyacetone kinase, phosphotransfer subunit; TIGRFAM: Dihydroxyacetone kinase, subunit phosphotransferase; PFAM: Phosphotransferase system, fructose subfamily IIA component.
 
  
 0.597
AEM78456.1
PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase.
   
 
 0.589
AEM79372.1
KEGG: thx:Thet_1891 dihydroxyacetone kinase, DhaK subunit; TIGRFAM: Dihydroxyacetone kinase DhaK, subunit 1; PFAM: Dak kinase.
  
  
 0.586
AEM79376.1
PFAM: FAD dependent oxidoreductase; BFD-like [2Fe-2S]-binding region; KEGG: tbo:Thebr_0552 FAD dependent oxidoreductase.
     
 0.571
AEM78512.1
PFAM: Glycerophosphoryl diester phosphodiesterase; KEGG: tbo:Thebr_0990 glycerophosphoryl diester phosphodiesterase.
  
 
 0.558
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.