STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFIntegral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (344 aa)    
Predicted Functional Partners:
AEM78011.1
PFAM: Spore germination protein-like Gmad2, bacteria; Lipoprotein LpqB, GerMN domain; KEGG: tmt:Tmath_0547 spore germination protein-like protein.
  
     0.735
AEM79382.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
     0.630
AEM79381.1
KEGG: thx:Thet_1900 delta-lactam-biosynthetic de-N-acetylase; TIGRFAM: Delta-lactam-biosynthetic de-N-acetylase; PFAM: Polysaccharide deacetylase.
  
    0.606
AEM77679.1
KEGG: tte:TTE0165 hypothetical protein; PFAM: Cell surface receptor IPT/TIG; Fibronectin, type III; SMART: Fibronectin, type III; Cell surface receptor IPT/TIG.
  
     0.584
AEM78702.1
KEGG: tbo:Thebr_1160 hypothetical protein.
  
     0.583
AEM78646.1
KEGG: tbo:Thebr_1106 hypothetical protein.
  
     0.577
AEM78645.1
PFAM: Fimbrial assembly; KEGG: tbo:Thebr_1105 fimbrial assembly family protein.
  
     0.573
AEM79038.1
KEGG: tbo:Thebr_0806 hypothetical protein.
  
     0.566
AEM79028.1
KEGG: thx:Thet_0909 hypothetical protein.
  
    0.529
AEM79367.1
KEGG: thx:Thet_1886 hypothetical protein.
 
     0.514
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.