STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79406.1PFAM: ABC-type uncharacterised transport system; KEGG: thx:Thet_1932 ABC-type uncharacterized transport system. (462 aa)    
Predicted Functional Partners:
AEM79407.1
PFAM: ABC-2 type transporter; KEGG: tbo:Thebr_0521 ABC-2 type transporter.
  
 0.979
AEM79408.1
KEGG: tbo:Thebr_0520 ABC transporter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core.
 
  
 0.961
AEM79405.1
KEGG: tmt:Tmath_1803 hypothetical protein.
 
     0.958
AEM78011.1
PFAM: Spore germination protein-like Gmad2, bacteria; Lipoprotein LpqB, GerMN domain; KEGG: tmt:Tmath_0547 spore germination protein-like protein.
  
     0.463
mprF
Integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
     0.406
AEM78269.1
PFAM: 4-oxalocrotonate tautomerase; KEGG: tmt:Tmath_0739 4-oxalocrotonate tautomerase.
 
     0.404
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.