STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
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Textmining
[Homology]
Score
AEM79422.1PFAM: Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal; UspA; KEGG: tbo:Thebr_0509 osmosensitive K channel His kinase sensor. (379 aa)    
Predicted Functional Partners:
kdpC
Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.939
kdpB
Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.934
kdpA
Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.929
AEM79800.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ctc:CTC01951 alkaline phosphatase synthesis sensor protein PhoR; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain.
 
 
 0.907
AEM79384.1
PFAM: Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal; UspA; KEGG: tte:TTE2009 osmosensitive K+ channel histidine kinase sensor subunit.
  
  
 
0.905
AEM78311.1
Manually curated; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; KEGG: tbo:Thebr_1572 ATP-binding region ATPase domain-containing protein; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain.
 
 
 0.890
AEM79900.1
Integral membrane sensor signal transduction histidine kinase; KEGG: tbo:Thebr_0171 ATP-binding region ATPase domain-containing protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain.
 
    
 0.890
AEM78544.1
Integral membrane sensor signal transduction histidine kinase; KEGG: tbo:Thebr_0281 ATP-binding region ATPase domain-containing protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain.
 
 
 0.705
AEM78993.1
Hypothetical protein; Manually curated.
 
 
 0.687
AEM79423.1
PFAM: Na+/H+ antiporter NhaC-like; KEGG: tbo:Thebr_0508 Na+/H+ antiporter NhaC-like protein.
       0.683
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.