STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79453.1Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (221 aa)    
Predicted Functional Partners:
AEM79651.1
KEGG: thx:Thet_2096 hypothetical protein.
  
 0.883
AEM79550.1
KEGG: tbo:Thebr_0458 thioredoxin reductase; TIGRFAM: Thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.800
AEM79959.1
KEGG: tbo:Thebr_0120 glutaredoxin-like protein, YruB-family; TIGRFAM: Glutaredoxin-like protein, YruB; PFAM: Glutaredoxin.
  
 
 0.757
AEM79375.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tmt:Tmath_1779 FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
  
 
 0.725
AEM79452.1
Sporulation protein YtaF; Probably functions as a manganese efflux pump.
       0.572
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.520
AEM78503.1
KEGG: tbo:Thebr_0984 PfpI familyintracellular protease; TIGRFAM: Peptidase C56, PfpI; PFAM: ThiJ/PfpI.
   
 
 0.469
AEM79817.1
Ferritin Dps family protein; Iron-storage protein.
  
  
 0.462
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.459
AEM78371.1
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.449
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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