STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79456.1PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: hor:Hore_22680 PfkB domain protein. (314 aa)    
Predicted Functional Partners:
AEM79454.1
KEGG: cbk:CLL_A3126 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: Carbohydrate/purine kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.972
AEM77719.1
KEGG: cbk:CLL_A3126 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: Carbohydrate/purine kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.930
AEM77807.1
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
  
 
 0.907
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.907
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 
 0.907
AEM79457.1
ABC-type transporter, integral membrane subunit; PFAM: Bacterial inner-membrane translocator; KEGG: str:Sterm_3539 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.802
rbsA
ABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
  
 0.742
AEM79459.1
PFAM: Periplasmic binding protein/LacI transcriptional regulator; KEGG: str:Sterm_3541 periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.726
AEM79455.1
KEGG: fructose-bisphosphate aldolase; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class II; Ketose-bisphosphate aldolase, class-II; PFAM: Ketose-bisphosphate aldolase, class-II.
  
  
 0.711
AEM79860.1
PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase; KEGG: thx:Thet_2299 iron-containing alcohol dehydrogenase.
  
 
 0.609
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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