Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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AEM79469.1Transcriptional regulator, AraC family; KEGG: hor:Hore_15370 helix-turn-helix-domain containing protein AraC type; PFAM: Helix-turn-helix, AraC type; Transcriptional regulator, histidine kinase sensor, N-terminal; SMART: Helix-turn-helix, AraC domain. (412 aa)    
Predicted Functional Partners:
AEM77976.1
KEGG: thx:Thet_0445 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; Cache; ATP-binding region, ATPase-like; SMART: HAMP linker domain.
 
  
 0.942
AEM77977.1
KEGG: tmt:Tmath_0510 two component transcriptional regulator, AraC family; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC domain.
 
  
 
0.922
AEM77787.1
KEGG: tmt:Tmath_0327 two component transcriptional regulator, AraC family; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; Signal transduction response regulator, receiver region.
 
  
 
0.916
AEM79468.1
KEGG: ate:Athe_2582 methionine synthase; TIGRFAM: Corrinoid methyltransferase, Methanosarcina species; PFAM: Cobalamin (vitamin B12)-binding; Methionine synthase, cobalamin (vitamin B12)-binding module, cap.
 
   
 0.872
AEM79470.1
Hypothetical protein; Manually curated.
 
     0.868
AEM79467.1
KEGG: dtu:Dtur_0731 uroporphyrinogen decarboxylase (URO-D); manually curated; PFAM: Uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family.
 
   
 0.857
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.744
AEM79860.1
PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase; KEGG: thx:Thet_2299 iron-containing alcohol dehydrogenase.
     
 0.719
AEM79471.1
KEGG: dsy:DSY1510 hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family.
 
   
 0.678
AEM79712.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: tbo:Thebr_0292 EAL domain-containing protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
  
  
 0.635
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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