Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79476.1PTS system transcriptional activator; KEGG: tbo:Thebr_1996 sigma-54 factor interaction domain-containing protein; PFAM: RNA polymerase sigma factor 54, interaction; PRD; Phosphotransferase system, fructose subfamily IIA component; SMART: ATPase, AAA+ type, core. (900 aa)    
Predicted Functional Partners:
AEM79091.1
KEGG: tbo:Thebr_0751 RNA polymerase sigma-54 factor, RpoN; TIGRFAM: RNA polymerase sigma factor 54; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54, core-binding; RNA polymerase sigma factor 54.
 
 
 
 0.826
AEM78139.1
PFAM: Phosphotransferase system, lactose/cellobiose-specific IIB subunit; KEGG: tbo:Thebr_1740 phosphotransferase system lactose/cellobiose-specific IIB subunit.
 
     0.692
AEM78140.1
PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
     0.667
AEM78141.1
PFAM: Phosphotransferase system, lactose/cellobiose-specific IIA subunit; KEGG: tbo:Thebr_1738 phosphotransferase system PTS lactose/cellobiose-specific IIA subunit.
 
   
 0.667
AEM77855.1
PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
     0.662
AEM77862.1
PFAM: Phosphotransferase system, lactose/cellobiose-specific IIA subunit; KEGG: tte:TTE0336 phosphotransferase system cellobiose-specific component IIA.
 
   
 0.657
AEM77854.1
KEGG: vfm:VFMJ11_0618 BglE; manually curated; PFAM: Phosphotransferase system, lactose/cellobiose-specific IIB subunit.
 
     0.652
AEM79474.1
PFAM: Phosphotransferase system, sorbose-specific IIC subunit; KEGG: str:Sterm_3024 phosphotransferase system PTS sorbose-specific IIC subunit.
 
  
 0.645
AEM79485.1
Manually curated; PFAM: Phosphotransferase system, fructose subfamily IIA component.
  
  
 0.624
AEM79648.1
PTS modulated transcriptional regulator, MtlR family; PFAM: PRD; Helix-turn-helix, type 11; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; KEGG: tbo:Thebr_0341 protein-N(pi)-phosphohistidine--sugar phosphotransferase.
 
   
 0.598
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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