node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEM77518.1 | AEM78538.1 | Thewi_0002 | Thewi_1112 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: tpd:Teth39_0987 hypothetical protein. | 0.823 |
AEM77518.1 | AEM79494.1 | Thewi_0002 | Thewi_2144 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | 0.985 |
AEM77518.1 | AEM79555.1 | Thewi_0002 | Thewi_2207 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III Xth; KEGG: tte:TTE2226 exonuclease III; TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; PFAM: Endonuclease/exonuclease/phosphatase. | 0.924 |
AEM77518.1 | AEM79850.1 | Thewi_0002 | Thewi_2523 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: tbo:Thebr_0221 PHP domain-containing protein; PFAM: PHP, C-terminal; SMART: DNA-directed DNA polymerase, family X; Helix-hairpin-helix DNA-binding motif, class 1; Polymerase/histidinol phosphatase, N-terminal. | 0.454 |
AEM77518.1 | AEM79857.1 | Thewi_0002 | Thewi_2532 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PHP domain protein; KEGG: tte:TTE2516 family X DNA polymerase IV; PFAM: PHP, C-terminal; SMART: DNA-directed DNA polymerase, family X; Helix-hairpin-helix DNA-binding motif, class 1; Polymerase/histidinol phosphatase, N-terminal. | 0.454 |
AEM77518.1 | polA | Thewi_0002 | Thewi_0961 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.997 |
AEM77543.1 | AEM79494.1 | Thewi_0027 | Thewi_2144 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | 0.724 |
AEM77765.1 | AEM79494.1 | Thewi_0264 | Thewi_2144 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | 0.643 |
AEM77765.1 | polA | Thewi_0264 | Thewi_0961 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | 5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.970 |
AEM78538.1 | AEM77518.1 | Thewi_1112 | Thewi_0002 | KEGG: tpd:Teth39_0987 hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.823 |
AEM78538.1 | AEM79494.1 | Thewi_1112 | Thewi_2144 | KEGG: tpd:Teth39_0987 hypothetical protein. | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | 0.677 |
AEM78538.1 | polA | Thewi_1112 | Thewi_0961 | KEGG: tpd:Teth39_0987 hypothetical protein. | 5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.938 |
AEM79492.1 | AEM79494.1 | Thewi_2142 | Thewi_2144 | KEGG: tbo:Thebr_0489 peptidoglycan-binding domain 1 protein; PFAM: Peptidoglycan binding-like; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup. | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | 0.612 |
AEM79492.1 | ku | Thewi_2142 | Thewi_2143 | KEGG: tbo:Thebr_0489 peptidoglycan-binding domain 1 protein; PFAM: Peptidoglycan binding-like; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup. | DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.588 |
AEM79494.1 | AEM77518.1 | Thewi_2144 | Thewi_0002 | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.985 |
AEM79494.1 | AEM77543.1 | Thewi_2144 | Thewi_0027 | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | 0.724 |
AEM79494.1 | AEM77765.1 | Thewi_2144 | Thewi_0264 | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | 0.643 |
AEM79494.1 | AEM78538.1 | Thewi_2144 | Thewi_1112 | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | KEGG: tpd:Teth39_0987 hypothetical protein. | 0.677 |
AEM79494.1 | AEM79492.1 | Thewi_2144 | Thewi_2142 | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | KEGG: tbo:Thebr_0489 peptidoglycan-binding domain 1 protein; PFAM: Peptidoglycan binding-like; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup. | 0.612 |
AEM79494.1 | AEM79555.1 | Thewi_2144 | Thewi_2207 | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | Exodeoxyribonuclease III Xth; KEGG: tte:TTE2226 exonuclease III; TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; PFAM: Endonuclease/exonuclease/phosphatase. | 0.887 |