Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM79514.1KEGG: cob:COB47_1659 integrase catalytic region; manually curated; PFAM: Integrase, catalytic core. (419 aa)    
Predicted Functional Partners:
AEM79513.1
KEGG: ckn:Calkro_2507 IstB domain-containing protein ATP-binding protein; manually curated; PFAM: IstB-like ATP-binding protein.
 
 0.961
AEM79725.1
KEGG: ckn:Calkro_2507 IstB domain-containing protein ATP-binding protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core.
 
 0.833
AEM78033.1
KEGG: ckn:Calkro_2507 IstB domain-containing protein ATP-binding protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core.
 
 0.820
AEM77866.1
KEGG: chy:CHY_1116 ISChy4, transposition helper protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core.
 
 
 0.818
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (18%) [HD]