STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79526.1PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: thx:Thet_1970 pyruvate/ketoisovalerate oxidoreductase, catalytic domain-containing protein. (191 aa)    
Predicted Functional Partners:
AEM77965.1
KEGG: tbo:Thebr_1890 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
 
 0.988
AEM79527.1
Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
 
 
 0.985
AEM79696.1
KEGG: tmt:Tmath_2023 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 
 0.982
AEM79530.1
PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: tbo:Thebr_0478 thiamine pyrophosphate TPP-binding domain-containing protein.
 
 
 0.882
AEM79531.1
PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal; KEGG: thx:Thet_1975 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
 
 
 0.867
AEM79528.1
PFAM: Phosphate acetyl/butaryl transferase; KEGG: tmt:Tmath_1871 phosphate acetyl/butaryl transferase.
     
 0.712
AEM78718.1
PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal; KEGG: tbo:Thebr_1178 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
 
 
 0.704
AEM79532.1
PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tit:Thit_1914 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
 
 0.696
AEM79529.1
KEGG: tbo:Thebr_0479 pyruvate/ketoisovalerate oxidoreductase subunit gamma; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
 
     0.690
AEM78719.1
PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: tbo:Thebr_1179 thiamine pyrophosphate TPP-binding domain-containing protein.
  
 
 0.684
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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