Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEM79531.1PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal; KEGG: thx:Thet_1975 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. (355 aa)    
Predicted Functional Partners:
AEM77965.1
KEGG: tbo:Thebr_1890 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
0.999
AEM79529.1
KEGG: tbo:Thebr_0479 pyruvate/ketoisovalerate oxidoreductase subunit gamma; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
 
 0.998
AEM79530.1
PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: tbo:Thebr_0478 thiamine pyrophosphate TPP-binding domain-containing protein.
 
 0.998
AEM79532.1
PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tit:Thit_1914 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
 0.995
AEM79696.1
KEGG: tmt:Tmath_2023 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
0.995
AEM78719.1
PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; KEGG: tbo:Thebr_1179 thiamine pyrophosphate TPP-binding domain-containing protein.
 
 0.992
AEM78720.1
KEGG: tbo:Thebr_1180 pyruvate/ketoisovalerate oxidoreductase subunit gamma; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
 
 0.985
AEM79177.1
KEGG: thx:Thet_1715 pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region.
    
 0.938
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.935
AEM79860.1
PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase; KEGG: thx:Thet_2299 iron-containing alcohol dehydrogenase.
  
 0.935
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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