STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79535.1PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region; Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; KEGG: thx:Thet_1979 Glu/Leu/Phe/Val dehydrogenase dimerization region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (355 aa)    
Predicted Functional Partners:
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.922
ilvD
TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: tit:Thit_0019 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
   
 0.912
AEM79120.1
KEGG: cce:Ccel_1264 dihydroxy-acid and 6-phosphogluconate dehydratase; manually curated; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
   
 0.912
AEM77531.1
PFAM: Pyruvate carboxyltransferase; KEGG: tbo:Thebr_0015 pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.907
AEM79167.1
KEGG: thx:Thet_1706 2-isopropylmalate synthase/homocitrate synthase family protein; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase related; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.907
buk-3
TIGRFAM: Butyrate kinase; HAMAP: butyrate kinase; KEGG: thx:Thet_1981 butyrate kinase; PFAM: Acetate/butyrate kinase; Belongs to the acetokinase family.
  
  
 0.876
buk-2
TIGRFAM: Butyrate kinase; HAMAP: butyrate kinase; KEGG: tbo:Thebr_0474 butyrate kinase; PFAM: Acetate/butyrate kinase; Belongs to the acetokinase family.
  
  
 0.841
AEM79536.1
KEGG: tbo:Thebr_0472 phosphate butyryltransferase; TIGRFAM: Phosphate butyryltransferase; PFAM: Phosphate acetyl/butaryl transferase.
  
  
 0.840
AEM78168.1
PFAM: Glutamate synthase, central-C; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tbo:Thebr_1700 glutamate synthase (NADPH).
  
 
 0.819
AEM79528.1
PFAM: Phosphate acetyl/butaryl transferase; KEGG: tmt:Tmath_1871 phosphate acetyl/butaryl transferase.
  
  
 0.727
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.