Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dacAConserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (277 aa)    
Predicted Functional Partners:
AEM79538.1
YbbR family protein; PFAM: YbbR-like; KEGG: thx:Thet_1982 YbbR family protein.
 
  
 0.964
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
 
 0.839
AEM78289.1
PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; KEGG: tbo:Thebr_1593 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II.
   
 
 0.814
AEM79998.1
PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; KEGG: tte:TTE2704 phosphomannomutase.
   
 
 0.720
AEM79389.1
PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; KEGG: thx:Thet_1903 nucleotidyl transferase.
   
 
 0.715
mutS2
MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.603
AEM79540.1
PFAM: Transposase, IS4-like; KEGG: has:Halsa_0720 hypothetical protein.
       0.522
AEM79529.1
KEGG: tbo:Thebr_0479 pyruvate/ketoisovalerate oxidoreductase subunit gamma; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
 
     0.508
AEM78769.1
PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: thx:Thet_1257 phosphoesterase RecJ domain-containing protein.
 
   
 0.481
buk-3
TIGRFAM: Butyrate kinase; HAMAP: butyrate kinase; KEGG: thx:Thet_1981 butyrate kinase; PFAM: Acetate/butyrate kinase; Belongs to the acetokinase family.
       0.481
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.