Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEM79551.1PFAM: Spore coat protein CotF-like; KEGG: tbo:Thebr_0457 coat F domain-containing protein. (91 aa)    
Predicted Functional Partners:
AEM79552.1
KEGG: tbo:Thebr_0456 hypothetical protein.
       0.752
AEM79554.1
Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
 
     0.616
AEM79028.1
KEGG: thx:Thet_0909 hypothetical protein.
  
     0.613
AEM79038.1
KEGG: tbo:Thebr_0806 hypothetical protein.
  
     0.591
AEM79553.1
PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; KEGG: tbo:Thebr_0455 MazG nucleotide pyrophosphohydrolase.
       0.555
AEM79550.1
KEGG: tbo:Thebr_0458 thioredoxin reductase; TIGRFAM: Thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
       0.544
AEM79975.1
KEGG: tit:Thit_2313 hypothetical protein.
  
     0.494
AEM79897.1
KEGG: thx:Thet_2334 hypothetical protein.
  
     0.482
AEM78011.1
PFAM: Spore germination protein-like Gmad2, bacteria; Lipoprotein LpqB, GerMN domain; KEGG: tmt:Tmath_0547 spore germination protein-like protein.
  
     0.479
AEM78463.1
KEGG: tbo:Thebr_1436 stage II sporulation protein P; TIGRFAM: Sporulation stage II, protein P; PFAM: Sporulation stage II, protein P.
  
     0.469
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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