STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79553.1PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; KEGG: tbo:Thebr_0455 MazG nucleotide pyrophosphohydrolase. (104 aa)    
Predicted Functional Partners:
AEM79554.1
Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.754
AEM79552.1
KEGG: tbo:Thebr_0456 hypothetical protein.
       0.581
AEM79551.1
PFAM: Spore coat protein CotF-like; KEGG: tbo:Thebr_0457 coat F domain-containing protein.
       0.560
AEM78004.1
KEGG: tbo:Thebr_1846 hypothetical protein.
  
     0.529
AEM78348.1
KEGG: thx:Thet_0753 hypothetical protein.
  
     0.487
AEM79627.1
KEGG: tbo:Thebr_0360 hypothetical protein.
  
     0.473
AEM78377.1
PFAM: Peptidase M4, propeptide, PepSY; S-layer homology region; KEGG: tit:Thit_0804 propeptide PepSY amd peptidase M4.
  
     0.462
AEM77760.1
PFAM: Sodium/calcium exchanger membrane region; KEGG: tte:TTE0262 Ca2+/Na+ antiporter.
 
     0.449
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.448
AEM79550.1
KEGG: tbo:Thebr_0458 thioredoxin reductase; TIGRFAM: Thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.415
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.