Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79620.1RNA polymerase, sigma-24 subunit, SigH, ECF subfamily; KEGG: tbo:Thebr_0367 RNA polymerase sigma-H factor; TIGRFAM: RNA polymerase sigma-H type; RNA polymerase sigma-70; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma factor 70, region 4 type 2. (214 aa)    
Predicted Functional Partners:
AEM79621.1
PFAM: Protein of unknown function DUF901; KEGG: tbo:Thebr_0366 hypothetical protein.
  
    0.784
mrnC
Ribonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
  
    0.762
AEM79622.1
KEGG: tbo:Thebr_0365 TrmH family RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
    0.760
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.693
cysS
KEGG: tbo:Thebr_0363 cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.686
AEM79609.1
PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: tbo:Thebr_0378 50S ribosomal protein L7Ae/L30e/S12e/Gadd45.
 
    0.670
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.667
AEM79625.1
TIGRFAM: Serine O-acetyltransferase; KEGG: tbo:Thebr_0362 serine O-acetyltransferase.
     
 0.658
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.638
AEM78389.1
KEGG: tmt:Tmath_0849 putative transmembrane anti-sigma factor.
  
 
 0.632
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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