| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM78528.1 | AEM78529.1 | Thewi_1102 | Thewi_1103 | KEGG: tbo:Thebr_1005 L-serine dehydratase, iron-sulfur-dependent subunit beta; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase beta subunit; PFAM: Serine dehydratase beta chain; Amino acid-binding ACT. | KEGG: tbo:Thebr_1006 L-serine dehydratase, iron-sulfur-dependent subunit alpha; TIGRFAM: L-serine dehydratase, alpha subunit; PFAM: Serine dehydratase alpha chain. | 0.999 |
| AEM78528.1 | AEM79625.1 | Thewi_1102 | Thewi_2277 | KEGG: tbo:Thebr_1005 L-serine dehydratase, iron-sulfur-dependent subunit beta; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase beta subunit; PFAM: Serine dehydratase beta chain; Amino acid-binding ACT. | TIGRFAM: Serine O-acetyltransferase; KEGG: tbo:Thebr_0362 serine O-acetyltransferase. | 0.908 |
| AEM78528.1 | glyA | Thewi_1102 | Thewi_2026 | KEGG: tbo:Thebr_1005 L-serine dehydratase, iron-sulfur-dependent subunit beta; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase beta subunit; PFAM: Serine dehydratase beta chain; Amino acid-binding ACT. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.959 |
| AEM78528.1 | thrB | Thewi_1102 | Thewi_2605 | KEGG: tbo:Thebr_1005 L-serine dehydratase, iron-sulfur-dependent subunit beta; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase beta subunit; PFAM: Serine dehydratase beta chain; Amino acid-binding ACT. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.828 |
| AEM78529.1 | AEM78528.1 | Thewi_1103 | Thewi_1102 | KEGG: tbo:Thebr_1006 L-serine dehydratase, iron-sulfur-dependent subunit alpha; TIGRFAM: L-serine dehydratase, alpha subunit; PFAM: Serine dehydratase alpha chain. | KEGG: tbo:Thebr_1005 L-serine dehydratase, iron-sulfur-dependent subunit beta; TIGRFAM: Iron-sulphur-dependent L-serine dehydratase beta subunit; PFAM: Serine dehydratase beta chain; Amino acid-binding ACT. | 0.999 |
| AEM78529.1 | AEM79625.1 | Thewi_1103 | Thewi_2277 | KEGG: tbo:Thebr_1006 L-serine dehydratase, iron-sulfur-dependent subunit alpha; TIGRFAM: L-serine dehydratase, alpha subunit; PFAM: Serine dehydratase alpha chain. | TIGRFAM: Serine O-acetyltransferase; KEGG: tbo:Thebr_0362 serine O-acetyltransferase. | 0.908 |
| AEM78529.1 | glyA | Thewi_1103 | Thewi_2026 | KEGG: tbo:Thebr_1006 L-serine dehydratase, iron-sulfur-dependent subunit alpha; TIGRFAM: L-serine dehydratase, alpha subunit; PFAM: Serine dehydratase alpha chain. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.959 |
| AEM78529.1 | thrB | Thewi_1103 | Thewi_2605 | KEGG: tbo:Thebr_1006 L-serine dehydratase, iron-sulfur-dependent subunit alpha; TIGRFAM: L-serine dehydratase, alpha subunit; PFAM: Serine dehydratase alpha chain. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.841 |
| AEM78573.1 | AEM79207.1 | Thewi_1150 | Thewi_1817 | KEGG: tbo:Thebr_1034 cysteine synthase A; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: tit:Thit_2087 cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.902 |
| AEM78573.1 | AEM79625.1 | Thewi_1150 | Thewi_2277 | KEGG: tbo:Thebr_1034 cysteine synthase A; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | TIGRFAM: Serine O-acetyltransferase; KEGG: tbo:Thebr_0362 serine O-acetyltransferase. | 0.990 |
| AEM78573.1 | cysS | Thewi_1150 | Thewi_2276 | KEGG: tbo:Thebr_1034 cysteine synthase A; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: tbo:Thebr_0363 cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.908 |
| AEM79207.1 | AEM78573.1 | Thewi_1817 | Thewi_1150 | KEGG: tit:Thit_2087 cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: tbo:Thebr_1034 cysteine synthase A; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.902 |
| AEM79207.1 | AEM79625.1 | Thewi_1817 | Thewi_2277 | KEGG: tit:Thit_2087 cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | TIGRFAM: Serine O-acetyltransferase; KEGG: tbo:Thebr_0362 serine O-acetyltransferase. | 0.990 |
| AEM79207.1 | cysS | Thewi_1817 | Thewi_2276 | KEGG: tit:Thit_2087 cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: tbo:Thebr_0363 cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.882 |
| AEM79621.1 | AEM79622.1 | Thewi_2273 | Thewi_2274 | PFAM: Protein of unknown function DUF901; KEGG: tbo:Thebr_0366 hypothetical protein. | KEGG: tbo:Thebr_0365 TrmH family RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.971 |
| AEM79621.1 | AEM79625.1 | Thewi_2273 | Thewi_2277 | PFAM: Protein of unknown function DUF901; KEGG: tbo:Thebr_0366 hypothetical protein. | TIGRFAM: Serine O-acetyltransferase; KEGG: tbo:Thebr_0362 serine O-acetyltransferase. | 0.853 |
| AEM79621.1 | cysS | Thewi_2273 | Thewi_2276 | PFAM: Protein of unknown function DUF901; KEGG: tbo:Thebr_0366 hypothetical protein. | KEGG: tbo:Thebr_0363 cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; PFAM: Cysteinyl-tRNA synthetase, class Ia, N-terminal; Cysteinyl-tRNA synthetase, class Ia, DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.912 |
| AEM79621.1 | mrnC | Thewi_2273 | Thewi_2275 | PFAM: Protein of unknown function DUF901; KEGG: tbo:Thebr_0366 hypothetical protein. | Ribonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.971 |
| AEM79622.1 | AEM79621.1 | Thewi_2274 | Thewi_2273 | KEGG: tbo:Thebr_0365 TrmH family RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | PFAM: Protein of unknown function DUF901; KEGG: tbo:Thebr_0366 hypothetical protein. | 0.971 |
| AEM79622.1 | AEM79625.1 | Thewi_2274 | Thewi_2277 | KEGG: tbo:Thebr_0365 TrmH family RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | TIGRFAM: Serine O-acetyltransferase; KEGG: tbo:Thebr_0362 serine O-acetyltransferase. | 0.859 |