Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79640.1Transcriptional repressor, CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes; KEGG: tbo:Thebr_0349 Firmicute transcriptional repressor of class III stress genes; Belongs to the CtsR family. (173 aa)    
Predicted Functional Partners:
AEM79639.1
PFAM: UvrB/UvrC protein; KEGG: tbo:Thebr_0350 UvrB/UvrC protein.
 
  
 0.993
mcsB
ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins.
 
  
 0.983
AEM79637.1
KEGG: tbo:Thebr_0352 ATPase AAA-2 domain-containing protein; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; UvrB/UvrC protein; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; Belongs to the ClpA/ClpB family.
  
  
 0.945
AEM79632.1
KEGG: tbo:Thebr_0355 PilT protein domain-containing protein; PFAM: PilT protein, N-terminal; Deoxyribonuclease/rho motif-related TRAM; SMART: Nucleotide binding protein, PINc.
 
    0.568
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.560
AEM79636.1
KEGG: tmt:Tmath_1956 iron (metal) dependent repressor, DtxR family; PFAM: Iron dependent repressor; SMART: Iron dependent repressor.
     
 0.543
AEM79641.1
KEGG: tmt:Tmath_1961 hypothetical protein.
       0.516
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
  
 0.503
AEM79434.1
Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system.
  
     0.500
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
   
  
 0.479
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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