STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79679.1KEGG: tbo:Thebr_0313 hypothetical protein. (121 aa)    
Predicted Functional Partners:
AEM79659.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
     0.914
AEM79658.1
KEGG: tbo:Thebr_0331 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
  
  
 0.787
folE
TIGRFAM: GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; KEGG: tbo:Thebr_0329 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.
  
  
 0.787
fhs
KEGG: thx:Thet_2122 formate--tetrahydrofolate ligase; HAMAP: Formate-tetrahydrofolate ligase, FTHFS; PFAM: Formate-tetrahydrofolate ligase, FTHFS.
  
  
 0.770
AEM79681.1
KEGG: thx:Thet_2123 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS.
       0.693
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.604
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.579
ftsH-2
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.551
AEM79676.1
LAO/AO transport system ATPase; KEGG: tte:TTE2387 periplasmic protein kinase ArgK; TIGRFAM: ArgK protein; PFAM: ArgK protein.
       0.519
AEM79678.1
methylmalonyl-CoA mutase, large subunit; KEGG: tte:TTE2389 methylmalonyl-CoA mutase N-terminal domain-containing protein; TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic.
       0.516
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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