Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79681.1KEGG: thx:Thet_2123 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS. (461 aa)    
Predicted Functional Partners:
AEM79649.1
Diguanylate cyclase with GAF sensor; TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; GAF; KEGG: tbo:Thebr_0340 diguanylate cyclase; SMART: Diguanylate cyclase, predicted; GAF.
 
 
 
 0.901
AEM78812.1
PFAM: Flagellar hook capping protein; KEGG: tbo:Thebr_1279 flagellar hook capping protein.
   
    0.800
AEM78976.1
KEGG: thx:Thet_0959 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
 
   
 0.777
AEM79728.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; KEGG: bmd:BMD_0935 response regulator diguanylate cyclase/phosphodiesterase; SMART: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region.
 
 
 
 0.765
AEM79559.1
Response regulator receiver protein; KEGG: tte:TTE1038 CheY-like domain-containing protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
 
   
 0.742
fhs
KEGG: thx:Thet_2122 formate--tetrahydrofolate ligase; HAMAP: Formate-tetrahydrofolate ligase, FTHFS; PFAM: Formate-tetrahydrofolate ligase, FTHFS.
       0.737
AEM78537.1
KEGG: tte:TTE1017 sensory transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain.
 
 
 
 0.733
AEM79063.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Signal transduction response regulator, receiver region; Diguanylate cyclase, predicted; KEGG: tpd:Teth39_0760 response regulator receiver modulated diguanylate cyclase; SMART: Signal transduction response regulator, receiver region; Diguanylate cyclase, predicted.
 
   
 0.727
AEM79712.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: tbo:Thebr_0292 EAL domain-containing protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
  
 
 0.708
AEM79679.1
KEGG: tbo:Thebr_0313 hypothetical protein.
       0.689
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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