Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79926.1KEGG: tmt:Tmath_2173 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT. (533 aa)    
Predicted Functional Partners:
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 
 0.903
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.903
AEM79927.1
PFAM: Aminotransferase, class V/Cysteine desulfurase; KEGG: thx:Thet_2356 class I/II aminotransclass V aminotransferase.
 
  
 0.885
AEM79925.1
KEGG: tmt:Tmath_2172 hypothetical protein.
       0.566
AEM79931.1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
  
 0.461
AEM79928.1
KEGG: tte:TTE2615 subtilisin-like serine protease; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; Protease-associated PA; Peptidase S8A, DUF1034 C-terminal; Bacterial Ig-like, group 2; S-layer homology region; SMART: Bacterial Ig-like, group 2; Belongs to the peptidase S8 family.
       0.417
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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