STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79927.1PFAM: Aminotransferase, class V/Cysteine desulfurase; KEGG: thx:Thet_2356 class I/II aminotransclass V aminotransferase. (360 aa)    
Predicted Functional Partners:
AEM79926.1
KEGG: tmt:Tmath_2173 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT.
 
  
 0.895
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
      0.646
purD
Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: tbo:Thebr_1748 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family.
  
    0.586
AEM79925.1
KEGG: tmt:Tmath_2172 hypothetical protein.
       0.552
AEM79863.1
KEGG: tbo:Thebr_0209 hypothetical protein.
  
 0.532
AEM78451.1
PFAM: Threonyl/alanyl tRNA synthetase, SAD; Alanyl-tRNA synthetase, class IIc, N-terminal; KEGG: tte:TTE0934 metal-dependent hydrolase.
  
  
 0.518
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.518
AEM77978.1
Formiminotransferase-cyclodeaminase; PFAM: Cyclodeaminase/cyclohydrolase; KEGG: thx:Thet_0447 formiminotransferase-cyclodeaminase.
  
  
 0.514
AEM79860.1
PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase; KEGG: thx:Thet_2299 iron-containing alcohol dehydrogenase.
  
 
 0.488
AEM79928.1
KEGG: tte:TTE2615 subtilisin-like serine protease; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; Protease-associated PA; Peptidase S8A, DUF1034 C-terminal; Bacterial Ig-like, group 2; S-layer homology region; SMART: Bacterial Ig-like, group 2; Belongs to the peptidase S8 family.
       0.440
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.