Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79968.1KEGG: tbo:Thebr_0111 HtrA2 peptidase; PFAM: Peptidase S1/S6, chymotrypsin/Hap; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF. (367 aa)    
Predicted Functional Partners:
AEM79967.1
KEGG: tbo:Thebr_0112 hypothetical protein.
       0.783
rlmH-2
Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.739
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.702
murA-3
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
   
 
 0.615
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
   0.612
AEM78072.1
Enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; KEGG: tte:TTE0544 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
    
 0.596
AEM79826.1
PFAM: Copper amine oxidase-like, N-terminal; KEGG: slp:Slip_1153 copper amine oxidase domain protein.
   
 0.573
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
 
 0.569
rpsH
Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
  
 
   0.562
rpsI
PFAM: Ribosomal protein S9; KEGG: tbo:Thebr_0419 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
   0.539
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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