Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79995.1PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; KEGG: thx:Thet_2406 FAD-dependent pyridine nucleotide-disulfide oxidoreductase. (451 aa)    
Predicted Functional Partners:
AEM78596.1
KEGG: thx:Thet_1433 beta-lactamase domain-containing protein.
  
 0.811
AEM77907.1
KEGG: tbo:Thebr_1962 sulfite reductase subunit C; TIGRFAM: Sulphite reductase, subunit C; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
     0.791
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
   
   0.668
AEM79860.1
PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase; KEGG: thx:Thet_2299 iron-containing alcohol dehydrogenase.
 
  
 0.622
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
   0.612
AEM79959.1
KEGG: tbo:Thebr_0120 glutaredoxin-like protein, YruB-family; TIGRFAM: Glutaredoxin-like protein, YruB; PFAM: Glutaredoxin.
     
 0.608
AEM79994.1
PFAM: Protein of unknown function DUF2179; Protein of unknown function DUF161; KEGG: tte:TTE2701 hypothetical protein.
       0.567
AEM78371.1
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.559
atpD
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
    
 
 0.551
AEM79996.1
PFAM: Capsule synthesis protein, CapA; KEGG: tte:TTE2703 putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation).
       0.548
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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