STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM80007.1ABC transporter transmembrane region; KEGG: tte:TTE2769 ABC-type multidrug/protein/lipid transport system, ATPase component; manually curated; PFAM: ABC transporter, transmembrane region. (577 aa)    
Predicted Functional Partners:
ecfA
ABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
    
0.734
ecfA-2
ABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
    
0.675
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.546
AEM77951.1
PFAM: Protein of unknown function DUF2210; KEGG: tbo:Thebr_1914 hypothetical protein.
  
     0.508
AEM79147.1
Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
  
    0.508
AEM79312.1
PFAM: Protein of unknown function DUF624; KEGG: thx:Thet_1851 hypothetical protein.
  
     0.500
AEM80008.1
Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1887 transposase IS4 family protein.
       0.496
AEM78606.1
Thioredoxin; KEGG: tbo:Thebr_1066 thioredoxin; TIGRFAM: Thioredoxin; PFAM: Thioredoxin domain.
  
    0.490
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
 
 
 0.479
AEM79806.1
PFAM: Uncharacterised conserved protein UCP028846; KEGG: thx:Thet_2249 hypothetical protein.
  
     0.476
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.