STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM80023.1KEGG: tbo:Thebr_2324 cyanophycin synthetase; TIGRFAM: Cyanophycin synthetase; PFAM: Mur ligase, central; Carbamoyl phosphate synthetase, large subunit, ATP-binding; ATP-grasp fold, RimK-type; Mur ligase, C-terminal; Belongs to the MurCDEF family. (876 aa)    
Predicted Functional Partners:
AEM80024.1
Cyanophycinase; KEGG: tbo:Thebr_2325 cyanophycinase; TIGRFAM: Cyanophycinase; PFAM: Peptidase S51, dipeptidase E.
 
  
 0.988
AEM79005.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
  
 0.922
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
  
0.922
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
 
 0.896
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
0.885
AEM79360.1
PFAM: Cell division protein FtsA domain; KEGG: tbo:Thebr_0568 cell division protein FtsA.
 
  
 0.870
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.870
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
  
 0.853
AEM78612.1
TIGRFAM: Conserved hypothetical protein CHP01319, GlmL; KEGG: thx:Thet_1421 hypothetical protein.
  
  
 0.812
AEM79013.1
SMART: PASTA; manually curated; TIGRFAM: Stage V sporulation protein D; KEGG: tbo:Thebr_0829 stage V sporulation protein D; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA.
  
 
 0.786
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.