STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM80029.1PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: thx:Thet_2453 cobyrinic acid a,c-diamide synthase. (255 aa)    
Predicted Functional Partners:
AEM80028.1
TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: thx:Thet_2452 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family.
 
 
 0.996
AEM80030.1
parB-like partition protein; SMART: ParB-like nuclease; manually curated; KEGG: thx:Thet_2454 ParB-like partition protein; TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; Belongs to the ParB family.
 
 
 0.969
dnaA
Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.626
AEM78757.1
Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1224 cell division protein FtsK/SpoIIIE.
  
  
 0.543
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
   
    0.504
rsmG
Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.468
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.459
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.455
AEM77963.1
Hypothetical protein; Manually curated.
   
 
 0.448
AEM78270.1
KEGG: thx:Thet_0686 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP02677; PFAM: Conserved hypothetical protein CHP02677.
   
 
 0.448
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.