STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM80030.1parB-like partition protein; SMART: ParB-like nuclease; manually curated; KEGG: thx:Thet_2454 ParB-like partition protein; TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; Belongs to the ParB family. (268 aa)    
Predicted Functional Partners:
AEM80029.1
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: thx:Thet_2453 cobyrinic acid a,c-diamide synthase.
 
 
 0.969
AEM80028.1
TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: thx:Thet_2452 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family.
 
   
0.853
rsmG
Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.819
AEM78757.1
Hypothetical protein; Manually curated; KEGG: tbo:Thebr_1224 cell division protein FtsK/SpoIIIE.
  
  
 0.736
AEM79533.1
KEGG: tbo:Thebr_0475 hypothetical protein.
  
 
 0.694
polA
5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.573
AEM80031.1
PFAM: NUDIX hydrolase domain; KEGG: tbo:Thebr_2332 NUDIX hydrolase.
       0.538
dnaA
Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
  
 0.493
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.452
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.