Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (413 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.909
ADU23673.1
PFAM: peptidase M16 domain protein; KEGG: cdl:CDR20291_2549 putative peptidase.
 
    0.835
ADU23672.1
PFAM: peptidase M16 domain protein; KEGG: csc:Csac_0914 peptidase M16 domain-containing protein.
  
    0.814
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.807
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
    0.650
ADU23741.1
KEGG: clo:HMPREF0868_1294 membrane protein insertase, YidC/Oxa1 family; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein.
  
  
 0.646
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.639
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
  
  
 0.599
gpsA
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: cce:Ccel_2129 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
    0.546
ADU23740.1
KEGG: cpy:Cphy_3942 single-stranded nucleic acid binding R3H domain-containing protein; PFAM: single-stranded nucleic acid binding R3H domain-containing protein; SMART: single-stranded nucleic acid binding R3H domain-containing protein.
  
    0.475
Your Current Organism:
Ruminococcus albus 7 DSM 20455
NCBI taxonomy Id: 697329
Other names: R. albus 7 = DSM 20455, Ruminococcus albus 7, Ruminococcus albus 7 = DSM 20455, Ruminococcus albus DSM 20455, Ruminococcus albus DSM 20455 = 7
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.