node1 | node2 | node1 annotation | node2 annotation | score |
A0A1V6P0A2 | A0A1V6P0R3 | CoA_binding domain-containing protein. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.967 |
A0A1V6P0A2 | A0A1V6P6J3 | CoA_binding domain-containing protein. | Transket_pyr domain-containing protein. | 0.977 |
A0A1V6P0A2 | A0A1V6P7C0 | CoA_binding domain-containing protein. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.853 |
A0A1V6P0A2 | A0A1V6P9H8 | CoA_binding domain-containing protein. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.878 |
A0A1V6P0A2 | A0A1V6PA19 | CoA_binding domain-containing protein. | Lipoyl-binding domain-containing protein. | 0.974 |
A0A1V6P0A2 | A0A1V6PB79 | CoA_binding domain-containing protein. | Cytochrome b5 heme-binding domain-containing protein. | 0.959 |
A0A1V6P0A2 | A0A1V6PIB7 | CoA_binding domain-containing protein. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.651 |
A0A1V6P0A2 | A0A1V6PJ70 | CoA_binding domain-containing protein. | Dihydrolipoyl dehydrogenase. | 0.827 |
A0A1V6P0A2 | A0A1V6PJT8 | CoA_binding domain-containing protein. | Peripheral subunit-binding (PSBD) domain-containing protein. | 0.898 |
A0A1V6P0A2 | A0A1V6PNC3 | CoA_binding domain-containing protein. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.485 |
A0A1V6P0R3 | A0A1V6P0A2 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | CoA_binding domain-containing protein. | 0.967 |
A0A1V6P0R3 | A0A1V6P6J3 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Transket_pyr domain-containing protein. | 0.977 |
A0A1V6P0R3 | A0A1V6P7C0 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.721 |
A0A1V6P0R3 | A0A1V6P9H8 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.967 |
A0A1V6P0R3 | A0A1V6PA19 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoyl-binding domain-containing protein. | 0.954 |
A0A1V6P0R3 | A0A1V6PB79 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Cytochrome b5 heme-binding domain-containing protein. | 0.768 |
A0A1V6P0R3 | A0A1V6PIB7 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.702 |
A0A1V6P0R3 | A0A1V6PJ70 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyl dehydrogenase. | 0.999 |
A0A1V6P0R3 | A0A1V6PJT8 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Peripheral subunit-binding (PSBD) domain-containing protein. | 0.956 |
A0A1V6P0R3 | A0A1V6PNC3 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.815 |