Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G7K_2101-t1Uncharacterized protein. (488 aa)    
Predicted Functional Partners:
G7K_2100-t1
CoA_binding domain-containing protein.
 
 
 0.998
G7K_4647-t1
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.976
G7K_4274-t1
Transket_pyr domain-containing protein.
  
 0.952
G7K_0595-t1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.951
G7K_6410-t1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.951
G7K_6367-t1
Uncharacterized protein.
   
 0.941
G7K_0610-t1
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.939
G7K_0676-t1
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.939
G7K_5101-t1
Uncharacterized protein.
     
 0.935
G7K_0147-t1
Uncharacterized protein; Belongs to the LDH/MDH superfamily.
  
 0.921
Your Current Organism:
Saitoella complicata
NCBI taxonomy Id: 698492
Other names: S. complicata NRRL Y-17804, Saitoella complicata CBS 7301, Saitoella complicata CCRC 22490, Saitoella complicata IAM 12963, Saitoella complicata JCM 7358, Saitoella complicata NBRC 10748, Saitoella complicata NRRL Y-17804
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