STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addAdenosine deaminase (Adenosine aminohydrolase); Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (339 aa)    
Predicted Functional Partners:
CCK77261.1
Phosphoribosyltransferase.
     
 0.936
xdhB
Putative xanthine dehydrogenase, XdhB subunit.
 
  
 0.931
xdhA
Xanthine dehydrogenase, XdhA subunit.
    
  0.913
CCK74688.1
Conserved hypothetical protein.
     
  0.900
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.900
guaA-2
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.645
CCK74246.1
Isopenicillin N synthase family protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.
  
    0.585
CCK77969.1
Putative 5'(3')-deoxyribonucleotidase.
     
  0.499
mtaP
5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
  
 
 0.497
CCK74386.1
Carbohydrate kinase.
    
 
 0.491
Your Current Organism:
Oleispira antarctica
NCBI taxonomy Id: 698738
Other names: O. antarctica RB-8, Oleispira antarctica DSM 14852, Oleispira antarctica RB-8, Oleispira antarctica str. RB-8, Oleispira antarctica strain RB-8
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