STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCK78072.1Transcriptional regulator, TrmB family. (243 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
   
    0.862
CCK76004.1
Hypothetical protein.
   
    0.862
CCK76431.1
Conserved hypothetical protein.
  
     0.523
glmU
Bifunctional protein GlmU (N-acetylglucosamine-1-phosphate uridyltransferase); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
       0.521
CCK78073.1
Exopolyphosphatase-related protein.
       0.520
CCK77638.1
Conserved hypothetical protein.
  
     0.495
CCK76378.1
Putative anti-sigma factor, ChrR family.
  
     0.463
CCK75673.1
Probable transcriptional regulator, TetR family.
  
     0.462
glmS
Glutamine-fructose-6-phosphate transaminase (isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
       0.460
CCK76192.1
3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase.
  
     0.453
Your Current Organism:
Oleispira antarctica
NCBI taxonomy Id: 698738
Other names: O. antarctica RB-8, Oleispira antarctica DSM 14852, Oleispira antarctica RB-8, Oleispira antarctica str. RB-8, Oleispira antarctica strain RB-8
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.