STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrBAspartate carbamoyltransferase. (303 aa)    
Predicted Functional Partners:
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
 
 0.999
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
 
 0.999
carA
Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
 
 0.999
Pogu_2742
Dihydroorotase-related cyclic amidohydrolase.
 0.999
Pogu_2464
Orotidine-5''-phosphate decarboxylase.
  
  
 0.991
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.989
Pogu_0443
Dihydroorotate dehydrogenase.
 
  
 0.988
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.953
Pogu_1279
Asparagine synthase (glutamine-hydrolyzing).
  
 
 0.945
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.917
Your Current Organism:
Pyrobaculum oguniense
NCBI taxonomy Id: 698757
Other names: P. oguniense TE7, Pyrobaculum oguniense JCM 10595, Pyrobaculum oguniense TE7, Pyrobaculum oguniense str. TE7, Pyrobaculum oguniense strain TE7
Server load: low (22%) [HD]