STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB89432.1Cyanophycin synthetase; InterProIPR011810:IPR011761:IPR018109:IPR003135:IPR 013221:IPR004101; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; KEGG: cyanophycin synthetase; SPTR: Cyanophycin synthetase; PFAM: Mur ligase middle domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; cytoplasmic peptidoglycan synthetase domain protein; TIGRFAM: cyanophycin synthetase; Belongs to the MurCDEF family. (875 aa)    
Predicted Functional Partners:
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
 
0.993
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
 
0.990
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
 
0.982
murG
UDP-N-acetylglucosamine-N- acetylmuramylpentapeptide N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
 0.978
SMB94365.1
Cell division protein FtsQ; Essential cell division protein.
  
  
 0.978
SMB91396.1
UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; InterPro IPR018481; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; KEGG: mta:Moth_0218 glycosyl transferase family protein; SPTR: Glycosyl transferase, family 4; PFAM: Glycosyl transferase, family 4, conserved region.
  
 
 0.974
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
 
 0.974
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
  
 0.959
SMB98127.1
Cell division protein FtsA; InterPro IPR003494; COGs: COG0849 Actin-like ATPase involved in cell division; KEGG: mta:Moth_1238 cell division protein FtsA; SPTR: Cell division protein FtsA; PFAM: cell division protein FtsA.
  
  
 0.959
SMB89416.1
Cyanophycinase; InterPro IPR011811:IPR005320; COGs: COG4242 Cyanophycinase and related exopeptidase; KEGG: cyanophycinase; PFAM: peptidase S51 dipeptidase E; PRIAM: Cyanophycinase; TIGRFAM: cyanophycinase; SPTR: Cyanophycinase; Belongs to the peptidase S51 family.
 
   
 0.956
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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