STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB89442.1Transcriptional regulator, GntR family; InterPro IPR000524:IPR000485:IPR011711; COGs: COG1802 Transcriptional regulators; KEGG: mta:Moth_0073 GntR family transcriptional regulator; SPTR: Transcriptional regulator, GntR family; SMART: regulatory protein GntR HTH; PFAM: GntR domain protein; regulatory protein GntR HTH. (232 aa)    
Predicted Functional Partners:
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
    
 0.781
SMB89449.1
MobA-like NTP transferase domain-containing protein; KEGG: mta:Moth_0074 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.669
SMB90724.1
Acetolactate synthase, small subunit; InterPro IPR002912:IPR019455:IPR004789; COGs: COG0440 Acetolactate synthase small (regulatory) subunit; KEGG: mta:Moth_2257 acetolactate synthase 3 regulatory subunit; SPTR: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; PRIAM: Acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit.
   
    0.635
prmC
[protein release factor]-glutamine N5-methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
   
   0.583
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
       0.555
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
       0.553
SMB90947.1
Propionaldehyde dehydrogenase; InterPro IPR015590; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; KEGG: aldehyde dehydrogenase; SPTR: Aldehyde Dehydrogenase; PFAM: Aldehyde Dehydrogenase.
  
 
 0.488
SMB89432.1
Cyanophycin synthetase; InterProIPR011810:IPR011761:IPR018109:IPR003135:IPR 013221:IPR004101; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; KEGG: cyanophycin synthetase; SPTR: Cyanophycin synthetase; PFAM: Mur ligase middle domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; cytoplasmic peptidoglycan synthetase domain protein; TIGRFAM: cyanophycin synthetase; Belongs to the MurCDEF family.
       0.437
SMB98582.1
Oxaloacetate decarboxylase, alpha subunit; InterProIPR001249:IPR000891:IPR003379:IPR000089:IPR 001882; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; KEGG: mta:Moth_1525 pyruvate carboxylase subunit B; SPTR: Acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein.
 
     0.402
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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