STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fdhDFdhD protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (259 aa)    
Predicted Functional Partners:
mobA
Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
 0.982
SMB90046.1
Formate dehydrogenase (NADP) alpha subunit; Contains selenocysteine; InterProIPR006478:IPR001041:IPR017896:IPR017900:IPR 006655:IPR019574:IPR006963:IPR006656:IPR006657; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; KEGG: mta:Moth_2312 formate dehydrogenase subunit alpha; SPTR: Formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; molydopterin dinucleotide-binding region; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated.
 
 
 0.961
SMB99093.1
InterPro IPR004435; COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; KEGG: mta:Moth_1819 molybdopterin-guanine dinucleotide biosynthesis protein B; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B.
 
 0.927
SMB89163.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterProIPR011895:IPR017896:IPR017900:IPR002880:IPR 019752:IPR019456:IPR011766; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: mta:Moth_0064 pyruvate:ferredoxin (flavodoxin) oxidoreductase; SPTR: Pyruvate:ferredoxin (Flavodoxin) oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing p [...]
    
 0.903
SMB98053.1
Nitrate reductase (quinol-dependent), catalytic subunit; InterPro IPR006963:IPR006656:IPR006657:IPR006655; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; KEGG: mta:Moth_1909 molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.896
moaA
Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
 0.884
SMB99933.1
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.868
SMB92471.1
Formate dehydrogenase major subunit; InterPro IPR006963:IPR006656:IPR006657; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; KEGG: dsy:DSY1990 putative anaerobic dehydrogenase; SPTR: Putative anaerobic dehydrogenase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.802
SMB90082.1
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; KEGG: pth:PTH_2648 NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit; SPTR: NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit; InterProIPR017896:IPR017900:IPR001949:IPR011538:IPR 019554:IPR019575; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone).
  
  
 0.794
SMB98921.1
NAD(P)-dependent iron-only hydrogenase iron-sulfur protein; SPTR: NADH dehydrogenase (Quinone); KEGG: mta:Moth_1718 NADH dehydrogenase (quinone).
  
  
 0.765
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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