STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB90331.1COGs: COG3885 conserved hypothetical protein; KEGG: mta:Moth_2295 hypothetical protein; SPTR: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; InterPro IPR002733:IPR004183; PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B. (462 aa)    
Predicted Functional Partners:
SMB90338.1
InterPro IPR016431:IPR007197; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; KEGG: mta:Moth_2294 radical SAM family protein; SPTR: Radical SAM; PFAM: Radical SAM domain protein.
 
     0.926
SMB90329.1
InterPro IPR002508; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; KEGG: mta:Moth_2296 N-acetylmuramoyl-L-alanine amidase; SPTR: N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin; PFAM: cell wall hydrolase/autolysin.
       0.663
nnrD
NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...]
  
  
 0.618
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
    0.512
SMB99050.1
InterPro IPR006638:IPR007197; COGs: COG0535 Fe-S oxidoreductase; KEGG: mta:Moth_1786 radical SAM family protein; SPTR: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; PFAM: Radical SAM domain protein.
  
     0.440
SMB99577.1
InterPro IPR016431:IPR007197; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; KEGG: adg:Adeg_0355 radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM domain protein.
 
     0.428
SMB90167.1
Hypothetical protein; InterPro IPR006076; COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; KEGG: mta:Moth_2310 FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase.
 
     0.402
SMB99926.1
MOSC domain-containing protein; InterPro IPR005302; COGs: COG2258 conserved hypothetical protein; KEGG: mta:Moth_2133 MOSC; SPTR: MOSC; PFAM: MOSC domain containing protein.
  
    0.402
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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