STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB90605.1Uncharacterized conserved protein YecE, DUF72 family; InterPro IPR002763; COGs: COG1801 conserved hypothetical protein; KEGG: adg:Adeg_1589 protein of unknown function DUF72; SPTR: Putative uncharacterized protein; PFAM: protein of unknown function DUF72. (245 aa)    
Predicted Functional Partners:
SMB99524.1
Bifunctional non-homologous end joining protein LigD; InterPro IPR002755:IPR014145; COGs: COG3285 eukaryotic-type DNA primase; KEGG: mta:Moth_2082 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: DNA primase small subunit; TIGRFAM: DNA polymerase LigD, polymerase domain protein.
 
    0.476
SMB90610.1
Predicted nucleotide-binding protein, sugar kinase/HSP70/actin superfamily; InterPro IPR018709; COGs: COG3580 conserved hypothetical protein; KEGG: mta:Moth_1742 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF2229, CoA enzyme activase.
       0.470
SMB90617.1
CoA-substrate-specific enzyme activase, putative; InterPro IPR002731:IPR008275; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); KEGG: mta:Moth_1743 CoA enzyme activase; SPTR: CoA enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; TIGRFAM: CoA-substrate-specific enzyme activase.
       0.470
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.445
SMB99518.1
DNA ligase-1; InterPro IPR012310:IPR012309:IPR014146; COGs: COG1793 ATP-dependent DNA ligase; KEGG: mta:Moth_1488 ATP dependent DNA ligase, central; SPTR: ATP dependent DNA ligase, central; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; TIGRFAM: DNA polymerase LigD, ligase domain protein.
 
    0.441
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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