STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB90979.1Two component transcriptional regulator, LytTR family; InterPro IPR001789:IPR007492; KEGG: mta:Moth_2172 LytR/AlgR family transcriptional regulator; SPTR: Transcriptional regulator, LytR/AlgR family; SMART: response regulator receiver; COGs: COG3279 Response regulator of the LytR/AlgR family; PFAM: response regulator receiver; LytTr DNA-binding region. (255 aa)    
Predicted Functional Partners:
SMB90982.1
Two-component system, LytT family, sensor kinase; InterProIPR003018:IPR003594:IPR010559:IPR005467:IPR 004358; COGs: COG3275 Putative regulator of cell autolysis; KEGG: mta:Moth_2171 ATP-binding region, ATPase-like; SPTR: ATP-binding region, ATPase-like; SMART: ATP-binding region ATPase domain protein; GAF domain protein; PFAM: histidine kinase internal region; GAF domain protein; ATP-binding region ATPase domain protein.
 0.989
SMB99135.1
Two-component system, LytT family, sensor histidine kinase LytS; InterProIPR005467:IPR003018:IPR003594:IPR011620:IPR 010559; COGs: COG3275 Putative regulator of cell autolysis; KEGG: adg:Adeg_0899 signal transduction histidine kinase, LytS; SPTR: Signal transduction histidine kinase, LytS; SMART: ATP-binding region ATPase domain protein; GAF domain protein; PFAM: histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; GAF domain protein; ATP-binding region ATPase domain protein.
 0.973
SMB99424.1
Two-component system, sensor histidine kinase YesM; InterProIPR003660:IPR004010:IPR010559:IPR003594:IPR 005467:IPR004358; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; KEGG: multi-sensor signal transduction histidine kinase; SPTR: Putative sensor with HAMP domain; SMART: histidine kinase HAMP region domain protein; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; Cache domain protein; ATP-binding region ATPase domain protein.
 
 
 0.898
SMB99488.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; InterPro IPR003660:IPR010559:IPR003594; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; KEGG: tex:Teth514_0223 integral membrane sensor signal transduction histidine kinase; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein.
 
 0.897
SMB99914.1
Hypothetical protein; InterProIPR003759:IPR006158:IPR018771:IPR010559:IPR 003594:IPR004358:IPR005467; COGs: COG5012 cobalamin binding protein; KEGG: mta:Moth_2114 histidine kinase; SPTR: Histidine kinase; SMART: ATP-binding region ATPase domain protein; PFAM: histidine kinase internal region; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; Transcription regulator,histidine kinase sensor-like; ATP-binding region ATPase domain protein.
 
 0.865
SMB98658.1
Hypothetical protein; InterPro IPR003594:IPR004358:IPR005467; COGs: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; KEGG: mta:Moth_1579 signal transduction histidine kinase regulating citrate/malate metabolism; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; SMART: ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein.
 
 
 0.671
SMB94630.1
Hypothetical protein; InterPro IPR003594:IPR005467:IPR004358; COGs: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; KEGG: mta:Moth_0904 signal transduction histidine kinase regulating citrate/malate metabolism; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; SMART: ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein.
  
 
 0.624
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.610
SMB99171.1
Transcriptional regulator, LytTR family; InterPro IPR007492:IPR018184; COGs: COG3279 Response regulator of the LytR/AlgR family; KEGG: mta:Moth_1621 LytR/AlgR family transcriptional regulator; SPTR: Transcriptional regulator, LytR/AlgR family; PFAM: LytTr DNA-binding region.
  
     0.560
SMB97683.1
Hypothetical protein; InterPro IPR004358:IPR003661:IPR003594:IPR005467; COGs: COG0642 Signal transduction histidine kinase; KEGG: mta:Moth_1138 histidine kinase; SPTR: Sensor protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
  
 
 0.559
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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