STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB91429.1PFAM: GGDEF domain containing protein; TIGRFAM: diguanylate cyclase; InterPro IPR000160; COGs: COG2199 FOG: GGDEF domain; KEGG: mta:Moth_0223 diguanylate cyclase; SPTR: Diguanylate cyclase (GGDEF domain); SMART: GGDEF domain containing protein. (377 aa)    
Predicted Functional Partners:
SMB98191.1
HD domain-containing protein; InterPro IPR006674; COGs: COG2206 HD-GYP domain; KEGG: diguanylate cyclase and metal dependent phosphohydrolase; SPTR: HD-GYP domain; PFAM: metal-dependent phosphohydrolase HD sub domain.
 0.965
SMB89663.1
HD domain-containing protein; InterPro IPR001789:IPR003607:IPR006674; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; KEGG: tye:THEYE_A0181 response regulator; SPTR: Response regulator; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain.
 
 
 0.955
SMB89410.1
Two-component system, OmpR family, response regulator; InterPro IPR001789:IPR001867; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; KEGG: mta:Moth_0070 two component transcriptional regulator; SPTR: Two component transcriptional regulator, winged helix family; SMART: response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain-containing protein.
 
 
 
 0.912
SMB99297.1
Two component transcriptional regulator, winged helix family; InterPro IPR005829:IPR001789:IPR001867; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; KEGG: mta:Moth_1131 two component transcriptional regulator; SPTR: Two component transcriptional regulator, winged helix family; SMART: response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain-containing protein.
 
 
 
 0.912
SMB95796.1
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant); InterPro IPR001633; COGs: COG2200 FOG: EAL domain; KEGG: mta:Moth_0346 diguanylate phosphodiesterase; SPTR: Diguanylate phosphodiesterase (EAL domain); SMART: EAL domain protein; PFAM: EAL domain protein.
 
 0.905
SMB96662.1
HD domain-containing protein; InterPro IPR006674:IPR003607; COGs: COG2206 HD-GYP domain; KEGG: tro:trd_0227 HD domain protein; SPTR: HD domain protein; SMART: metal-dependent phosphohydrolase HD region; PFAM: metal-dependent phosphohydrolase HD sub domain.
 
  0.857
SMB99636.1
Metal dependent phosphohydrolase; InterPro IPR003607:IPR006674; COGs: COG2206 HD-GYP domain; SPTR: Metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: mta:Moth_1432 metal dependent phosphohydrolase.
 
  0.823
SMB93154.1
Putative two-component system response regulator; InterPro IPR003607:IPR006674; COGs: COG2206 HD-GYP domain; KEGG: tle:Tlet_1338 metal dependent phosphohydrolase; SPTR: Metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region; PFAM: metal-dependent phosphohydrolase HD sub domain.
 0.806
SMB91434.1
Competence protein ComFA; InterPro IPR014001:IPR001650:IPR006935:IPR014021; COGs: COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein); KEGG: mta:Moth_0224 DEAD/DEAH box helicase-like; SPTR: DEAD/DEAH box helicase-like; SMART: DEAD-like helicase; helicase domain protein; PFAM: helicase domain protein; type III restriction protein res subunit.
       0.773
SMB91443.1
comF family protein; InterPro IPR000836; COGs: COG1040 amidophosphoribosyltransferase; KEGG: mta:Moth_0225 phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: phosphoribosyltransferase.
  
    0.764
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.