STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (262 aa)    
Predicted Functional Partners:
SMB91527.1
Glyceraldehyde-3-phosphate dehydrogenase (NAD+); InterProIPR020830:IPR020828:IPR020829:IPR020832:IPR 006424:IPR020831; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; KEGG: mta:Moth_0262 glyceraldehyde-3-phosphate dehydrogenase; SPTR: Glyceraldehyde-3-phosphate dehydrogenase; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the [...]
 0.999
pgk
Phosphoglycerate kinase; InterPro IPR015911:IPR001576; COGs: COG0126 3-phosphoglycerate kinase; KEGG: mta:Moth_0263 phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 0.999
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.998
SMB99149.1
Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794; COGs: COG0469 Pyruvate kinase; KEGG: mta:Moth_1867 pyruvate kinase; SPTR: Pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
 0.989
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 0.972
SMC00123.1
Fructose-bisphosphate aldolase; InterPro IPR000771:IPR015942:IPR011289; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; KEGG: mta:Moth_2404 fructose-1,6-bisphosphate aldolase; SPTR: Fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; Asp/Glu/hydantoin racemase; PRIAM: Tagatose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase.
  
 
 0.971
SMB90919.1
Fructose-bisphosphate aldolase, class II; InterPro IPR000771; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; KEGG: eok:G2583_4912 fructose-bisphosphate aldolase; SPTR: Putative aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase.
  
 
 0.946
SMB97280.1
Fructose-bisphosphate aldolase; InterPro IPR000771; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; KEGG: dsy:DSY1493 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase.
  
 
 0.946
SMB97459.1
Fructose-bisphosphate aldolase; InterPro IPR000771; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; KEGG: mta:Moth_0609 fructose-bisphosphate aldolase; SPTR: Fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase.
  
 
 0.946
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 0.914
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.