STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
SMB92761.1Carbon-monoxide dehydrogenase iron sulfur subunit; InterPro IPR017896:IPR017900; COGs: COG1142 Fe-S-cluster-containing hydrogenase components 2; KEGG: tte:TTE1707 Fe-S-cluster-containing hydrogenase components 1; SPTR: Fe-S-cluster-containing hydrogenase components 1. (161 aa)    
Predicted Functional Partners:
SMB92764.1
Ni-dependent carbon monoxide dehydrogenase precursor; InterPro IPR010047:IPR004137; COGs: COG1151 6Fe-6S prismane cluster-containing protein; KEGG: tte:TTE1708 carbon monoxide dehydrogenase subunit CooS; SPTR: Carbon monoxide dehydrogenase subunit CooS; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit.
 
  
 0.921
SMB89163.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterProIPR011895:IPR017896:IPR017900:IPR002880:IPR 019752:IPR019456:IPR011766; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: mta:Moth_0064 pyruvate:ferredoxin (flavodoxin) oxidoreductase; SPTR: Pyruvate:ferredoxin (Flavodoxin) oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing p [...]
  
 
 0.837
SMB93537.1
InterPro IPR006471; COGs: COG2864 Cytochrome b subunit of formate dehydrogenase; KEGG: mta:Moth_0452 formate dehydrogenase gamma subunit; SPTR: Formate dehydrogenase gamma subunit; TIGRFAM: formate dehydrogenase, gamma subunit.
  
 0.795
SMB93102.1
Hydrogenase small subunit; InterPro IPR001821:IPR017909:IPR006137:IPR006311; COGs: COG1740 Ni Fe-hydrogenase I small subunit; KEGG: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: Hydrogenase (acceptor); TIGRFAM: hydrogenase (NiFe) small subunit HydA; SPTR: Ni,Fe-hydrogenase small subunit.
  
 
 0.748
SMB90826.1
InterPro IPR006963:IPR006656:IPR006657; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; KEGG: mta:Moth_1243 molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 0.747
SMB91257.1
Anaerobic selenocysteine-containing dehydrogenase; PRIAM: Trimethylamine-N-oxide reductase (cytochrome c); InterPro IPR006963:IPR006656:IPR006657; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; KEGG: mta:Moth_1382 molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 0.747
SMB93523.1
Thiosulfate reductase / polysulfide reductase chain A; InterProIPR017909:IPR019546:IPR006963:IPR006656:IPR 006657:IPR006311:IPR006655; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; KEGG: mta:Moth_0450 formate dehydrogenase; SPTR: Formate dehydrogenase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; Twin-arginine translocation pathway, signal sequence, subgroup; molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 0.747
SMB93106.1
Hydrogenase large subunit; InterPro IPR001501:IPR018194; COGs: COG0374 Ni Fe-hydrogenase I large subunit; KEGG: dsy:DSY1598 Hup-type Ni,Fe-hydrogenase large subunit; SPTR: Hup-type Ni,Fe-hydrogenase large subunit; PFAM: nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.740
SMB90046.1
Formate dehydrogenase (NADP) alpha subunit; Contains selenocysteine; InterProIPR006478:IPR001041:IPR017896:IPR017900:IPR 006655:IPR019574:IPR006963:IPR006656:IPR006657; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; KEGG: mta:Moth_2312 formate dehydrogenase subunit alpha; SPTR: Formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; molydopterin dinucleotide-binding region; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated.
  
 
 0.730
SMB98053.1
Nitrate reductase (quinol-dependent), catalytic subunit; InterPro IPR006963:IPR006656:IPR006657:IPR006655; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; KEGG: mta:Moth_1909 molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.730
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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