STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB93354.1Enamidase; InterPro IPR006680; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; KEGG: nth:Nther_2144 amidohydrolase; SPTR: Enamidase; PFAM: amidohydrolase. (387 aa)    
Predicted Functional Partners:
SMB93366.1
6-hydroxynicotinate reductase; InterPro IPR017896:IPR017900; KEGG: nth:Nther_2148 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Putative uncharacterized protein.
 
  
  0.987
SMB93370.1
Hypothetical protein; InterPro IPR003374; COGs: COG2122 conserved hypothetical protein; KEGG: mno:Mnod_1250 ApbE family lipoprotein; SPTR: Putative uncharacterized protein; PFAM: ApbE family lipoprotein.
 
     0.927
SMB93377.1
Amino acid synthesis; InterPro IPR009569; KEGG: mag:amb1479 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: protein of unknown function DUF1185.
 
     0.918
SMB93400.1
2-methyleneglutarate mutase; InterPro IPR006158:IPR006159; COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); KEGG: nth:Nther_2157 2-methyleneglutarate mutase; SPTR: 2-methyleneglutarate mutase; PFAM: cobalamin B12-binding domain protein.
 
     0.806
SMB93386.1
2-hydroxymethylglutarate dehydrogenase; InterPro IPR006115:IPR011548:IPR002204:IPR006183; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; KEGG: nth:Nther_2161 3-hydroxyisobutyrate dehydrogenase; SPTR: Putative uncharacterized protein; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
    
  0.749
SMB92530.1
Tartronate semialdehyde reductase; InterPro IPR006115:IPR006398:IPR002204:IPR006183; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; KEGG: dda:Dd703_0845 2-hydroxy-3-oxopropionate reductase; SPTR: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; TIGRFAM: 2-hydroxy-3-oxopropionate reductase.
    
  0.585
SMB93418.1
Conserved hypothetical protein; InterPro IPR006230; KEGG: nth:Nther_2155 glutamate mutase, MutL; SPTR: Glutamate mutase, MutL.
 
     0.574
SMB99459.1
Purine hydroxylase beta subunit apoprotein; InterPro IPR008274; COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; KEGG: mta:Moth_1225 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; SPTR: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding.
  
     0.503
SMB93409.1
Methylitaconate delta2-delta3-isomerase; InterPro IPR007400; COGs: COG2828 conserved hypothetical protein; KEGG: nth:Nther_2156 protein of unknown function DUF453; PFAM: protein of unknown function DUF453; SPTR: Putative uncharacterized protein.
 
     0.477
SMB93427.1
2,3-dimethylmalate lyase; InterPro IPR000918:IPR018523; COGs: COG2513 PEP phosphonomutase; KEGG: aco:Amico_1318 carboxyvinyl-carboxyphosphonatephosphorylmutase; SPTR: Methylisocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase.
 
     0.458
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
Server load: low (18%) [HD]