STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB93733.12-oxoglutarate ferredoxin oxidoreductase subunit gamma; InterPro IPR019752; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; KEGG: mta:Moth_1986 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain. (175 aa)    
Predicted Functional Partners:
SMB89163.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterProIPR011895:IPR017896:IPR017900:IPR002880:IPR 019752:IPR019456:IPR011766; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: mta:Moth_0064 pyruvate:ferredoxin (flavodoxin) oxidoreductase; SPTR: Pyruvate:ferredoxin (Flavodoxin) oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing p [...]
  
 0.992
SMB93730.1
2-oxoglutarate ferredoxin oxidoreductase, beta subunit; InterPro IPR011766; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; KEGG: mta:Moth_1985 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein.
 
 0.980
SMB93726.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; InterPro IPR002880; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: mta:Moth_1984 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
 
 0.976
SMB88720.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta; InterPro IPR011766; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; KEGG: thiamine pyrophosphate protein domain protein TPP-binding protein; SPTR: 3-methyl-2-oxobutanoate dehydrogenase (Ferredoxin), beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein.
 
 0.941
SMB95272.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta; InterPro IPR011766; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; KEGG: adg:Adeg_1384 thiamine pyrophosphate protein domain protein TPP-binding protein; SPTR: Keto/oxoacid ferredoxin oxidoreductase, alpha subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein.
 
 0.940
SMB93724.1
NADPH-dependent glutamate synthase beta chain; InterPro IPR017896:IPR013027:IPR017900:IPR000759; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; KEGG: dal:Dalk_2523 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: BzdV; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.909
SMB88704.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; InterPro IPR002880:IPR005476; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: hor:Hore_06780 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), alpha subunit; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain-containing protein.
 
 0.901
SMB95258.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; InterPro IPR002880; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: 2-oxoacid:ferredoxin oxidoreductase, alpha subunit, putative; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
 
 0.899
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.869
SMB89241.1
InterPro IPR011766; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; KEGG: tye:THEYE_A0910 pyruvate synthase subunit PorB; SPTR: Thiamine pyrophosphate protein domain protein TPP-binding; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein.
  
 0.781
Your Current Organism:
Thermanaeromonas toyohensis
NCBI taxonomy Id: 698762
Other names: T. toyohensis ToBE, Thermanaeromonas toyohensis DSM 14490, Thermanaeromonas toyohensis ToBE, Thermanaeromonas toyohensis str. ToBE, Thermanaeromonas toyohensis strain ToBE, Thermoanaerobacter sp. ToBE
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